Category: eCysticFibrosis Review

In this podcast guest author Steven Rowe, MD, Associate Professor of Medicine from the University of Alabama at Birmingham, describes how CFTR modulator therapy fits into the clinical armamentarium of CF lung disease; identifies which patients are most appropriate for CF modulator treatment; and describes current research efforts and how to identify patients suitable for referral for consideration in CFTR modulator clinical trials.

In this podcast guest author Dr. Margaret Rosenfeld from the University of Washington School of Medicine, discusses the rationale for early Pseudomonas aeruginosa eradication, Identifies the inhaled and oral antibiotics that have been compared in clinical trials for early Pseudomonas eradication, and describes the potential adverse effects of early Pseudomonas eradication therapy.

In this podcast guest author Amanda Radmer Leonard, Pediatric Nutrition Practitioner, of the Johns Hopkins Children’s Center, describes approaches to the treatment of low vitamin D levels in patients with cystic fibrosis, discuss the variability of fecal elastase result during the first year of life, and summarizes the importance of tailoring nutritional interventions to specific patient and family situations.

Nonadherence to any medical regimen is common particularly among adolescents and young adults, and cystic fibrosis (CF) is no exception. There are many barriers to following the complex daily regimen that CF management requires, and researchers and clinicians have not yet found the ideal approach for counseling and supporting patients to improve and maintain their level of adherence. In this podcast Dr. Kristin Riekert, of The Johns Hopkins Adherence Research Center discusses best practices for determining which clinic patients are nonadherent and Identifies risk factors for nonadherence.