Antibiotics, Dosing, and CFTR

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Airway infections are a hallmark of cystic fibrosis, making antibiotic therapies a mainstay of CF treatment. While the fight against ABX resistance is ongoing, newer data are showing that commonly used dosing regimens may have to be altered to account for the particular pharmacodynamics in people with CF. How should ABX dosing be altered, and what additional effect might CFTR modulation have on dosing decisions?

That’s the topic Dr. Andrea Hahn, Assistant Professor of Pediatrics and an Infectious Disease Specialist at Children’s National Medical Center and George Washington University School of Medicine and Health Sciences, addresses in this eCysticFibrosis Review podcast. 

UPDATE 9/30/2020 – COVID-19 Infectious Disease Expert Interview

Dr. Paul Auwaerter interviews Dr. Michael G. Ison, Professor of Divisions of Infectious Diseases and Organ Transplantation, about his experience treating COVID-19. Topics: *Impact of COVID-19 in the Midwest region *How behavior impacts spread of infectious disease *Expectations of COVID-19 in the future *Gold standard of COVID-19 testing *Therapeutic procedures at Northwestern

UPDATE 9/25/2020 – COVID-19 Oncology Urgent Care and Biocontainment Part 2

MiKaela Olsen, DNP, APRN-CNS, AOCNS, FAAN and Gina Szymanski MS, RN discuss oncology urgent care during the COVID-19 pandemic. Topics: *Workflows for COVID-19 positive patients *Providing treatment for cancer patients that are also COVID-19+ *The biggest obstacles to setting up the biocontainment space *The key successes of the oncology urgent care center *Lessons learned and future goals

UPDATE 9/23/2020 – COVID-19: Keeping Up With A Moving Target

Dr. Auwaerter gives us an update and answers your COVID-19 questions. Topics covered: *The data on transmission in schools and childcare *How safe is flying? *The most important thing you can do to prevent infection *The latest vaccine information *Are restaurants safe?

UPDATE 9/18/2020 – COVID-19 Oncology Urgent Care and Biocontainment Part 1

MiKaela Olsen, DNP, APRN-CNS, AOCNS, FAAN and Gina Szymanski MS, RN discuss oncology urgent care during the COVID-19 pandemic. Topics: *Adapting the oncology urgent care when COVID-19 hit *Preventing the hospital from being overwhelmed *How Johns Hopkins Hospital handled staffing resources *Preventing infections between staff and patients 

UPDATE 9/16/2020 – COVID-19 and Substance Abuse Part 2

Dr. Paul Auwaerter interviews Dr. Kathleen Brady about… *How providers can help treat substance use disorders *Resources for treating addiction *Using telehealth to deliver substance use therapy *Tips for helping patients recognize a substance use issue

UPDATE 9/11/2020 – COVID-19 Challenges and Opportunities

David Reif, MSN, RN, CCRN discusses challenges during the COVID-19 pandemic and opportunities to overcome them. Topics:  *PAPRs, masks and shields *Family/caregiver presence *Special populations *Overburdened healthcare system *Communicating with international patients *Lack of technology 

MSM, PrEP, and STIs: The Clinical Perspective

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To read a companion newsletter click here.

Both the on-going syphilis and HIV epidemics are highly concentrated among men who have sex with men. While PrEP has been proven to reduce HIV transmission, it is not designed to prevent sexually transmitted infections like gonorrhea, syphilis, and chlamydia. What does the evidence say about reducing STI risk in MSM, and how can it be most effectively applied in practice? 

In this podcast, Dr. Matthew Spinelli — Assistant Professor in the Division of HIV, ID, and Global Medicine at the University of California, San Francisco and San Francisco General Hospital — takes us to the clinic to explain what providers can do to help their patients avoid acquiring and transmitting STIs. 

UPDATE 9/9/2020 – COVID-19 and Substance Abuse Part 1

Dr. Paul Auwaerter interviews Dr. Kathleen Brady about the impact of COVID-19 on substance abuse. Topics: *Substance abuse in the US *Impact on minority communities *Reasons overdoses have increased *The difficulty of funding substance abuse treatment centers *How Yale recognizes and identifies substance abuse disorder patients 

UPDATE 9/4/2020 – COVID-19 Challenges and Opportunities

Dr. Auwaerter gives us an update and answers your COVID-19 questions. Topics covered: *“The kids aren’t alright”? *The keys to returning to school *Issues with remdesivir and convalescent plasma EUAs *Do masks only protect others? *Questions about the CDC testing guidelines