Future Landscape of CFTR Modulators

Volume 6, Issue 12.

Claire Wainwright, FRACP, MD and Tonia Douglas, MD cover the important topic of the Future Landscape of CFTR Modulators in the format of case-study scenarios for the clinical practice.

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Featured Cases: Emerging Pathogens in Cystic Fibrosis

Volume 3, Issue 12.

Case studies offer opportunity to differentiate the needs of each patient when managing respiratory infections. Dr. Elliott Dasenbrook will review the prevalence of important CF organisms over the last 10 years, the impact of respiratory tract MRSA on survival, the association between a virulent strain of P. aeruginosa that can spread among patients and lung transplant or death, as well as the impact of chronic non-tuberculous Mycobacterial lung disease on lung function.

Featured Cases: Allergic Bronchopulmonary Aspergillosis (ABPA)

Volume 2, Issue 4.

In this edition Dr. Richard Moss will help expand our understanding of allergic bronchopulmonary aspergillosis (ABPA) with the discussion some typical case scenarios. ABPA is a major pulmonary complication in patients with cystic fibrosis (CF). The impact of ABPA on the course of CF lung disease poses special challenges, with chronic Aspergillus respiratory infection, even in the absence of ABPA, playing a significant role, according to data from 2 recent retrospective cohort studies. Dr. Moss’ use of current diagnostic criteria provides perspective also on the limitations.