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MSM, PrEP, and STIs: The Clinical Perspective

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Both the on-going syphilis and HIV epidemics are highly concentrated among men who have sex with men. While PrEP has been proven to reduce HIV transmission, it is not designed to prevent sexually transmitted infections like gonorrhea, syphilis, and chlamydia. What does the evidence say about reducing STI risk in MSM, and how can it be most effectively applied in practice? 

In this podcast, Dr. Matthew Spinelli — Assistant Professor in the Division of HIV, ID, and Global Medicine at the University of California, San Francisco and San Francisco General Hospital — takes us to the clinic to explain what providers can do to help their patients avoid acquiring and transmitting STIs. 

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Clinical Insights: Expanding HIV Testing and Treatment

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Our ability to reduce HIV infection and transmission depends on testing, in particular assessing the status of at-risk people who continue to remain untested.  

In this issue, Dr. Cedric Bien-Gund from the Division of Infectious Diseases at the University of Pennsylvania takes us to the clinic to explain the pros and cons of the currently available HIV tests and explains which are best to use in particular clinical circumstances. 

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In the Clinic: HIV and Aging

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In the US, nearly half of all people living with HIV are now aged 50 years or older. Their health care providers face new challenges in managing the effects of aging in their patients. In this eHIV Review podcast, Dr. Maile Young Karris from the University of California San Diego provides clinical insight into HIV and aging. 

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Two Drug ART? — Clinical Considerations

In her recent newsletter issue (eHIV Review V5 #1), Dr. Ethel Weld, Assistant Professor of Medicine, Pharmacology and Molecular Sciences at the Johns Hopkins School of Medicine, analyzed the current research about the potential uses of two-drug ART regimens. Join her now for a case-based discussion about how that new information can affect patient selection in the clinic.

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“U=U” — Clinical Considerations

Volume 4, Issue 12

“U=U” — an Undetectable HIV viral load means Untransmittable HIV virus.  In her recent eHIV Newsletter Issue (Vol. 4; No. 11), Dr. Jill Blumenthal from the Division of Infectious Diseases and Global Public Health at the University of California San Diego analyzed the current evidence strongly supporting this concept.  In this Podcast, she discusses “U=U” from the clinical perspective, and models how it can help promote patient safety.

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In Clinical Practice: Overcoming Patient Barriers to PrEP

Volume 1, Issue 2

In this issue:

PrEP — pre-exposure prophylaxis to prevent HIV transmission — is safe, it’s effective, and it’s significantly underused in the U.S.  One key barrier to increased PrEP use is a lack of awareness and acceptance among the patient populations most at-risk for new HIV infection.

In this podcast, Dr. Douglas Krakower from Harvard Medical School takes us into the exam room to translate the new information in his Newsletter Issue into clinical practice.

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Clinical Aspects of Improving ART Adherence

Volume 4, Issue 10

In this Issue, Dr. Joyce Jones from the Johns Hopkins University School of Medicine and Dr. Barbara Taylor from the University of Texas Health Science Center at San Antonio analyze recent publications describing evidence-based ART adherence interventions and how they can be tailored to specific situations to increase effectiveness.

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Clinical Perspective: New AEs from Newer ART

Volume 4, Issue 8

While newer antiviral agents like darunavir and the integrase strand transfer inhibitor (INSTI) dolutegravir have shown great efficacy, recent postmarketing surveillance has identified important adverse effects not found in the clinical trial populations.

In this issue, Dr. Cody Chastain from the Division of Infectious Diseases at Vanderbilt University Medical Center discusses how these new findings can impact the clinical use of these new agents.

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Clinical Challenges of Engaging PWID and MSM in HIV Care

Volume 4, Issue 6.

Linking high-risk populations like PWIDs (people who inject drugs) and MSM (men who have sex with men) to effective HIV care requires overcoming complex barriers unique to these groups.

In this issue, two of the directors from Boston’s Health Care for the Homeless Program, Dr. Jennifer Brody, Director of HIV Services and ANP Marguerite Beiser, Director of HCV Services, discuss the clinical aspects of addressing these challenges.

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In the Clinic: ART and Metabolic Effects

Volume 4, Issue 4.

The incidence of the metabolic complications common in people with HIV infection — bone disease, weight gain, cardiovascular disease, and liver disease — is increasing as improved antiretroviral therapies create longer lifespans.

In this issue, Dr. Suman Srinivasa and nurse practitioner Kathleen Fitch from Harvard Medical School discuss how to identify and manage these metabolic complications to help improve outcomes and quality of life in patients living with HIV.

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